Generic Name: Mesoridazine



Serentil (mesoridazine) is a typical antipsychotic medication that belongs to a group of drugs called phenothiazines. This medication was developed to help control the symptoms of schizophrenia, but it will not cure the condition. Serentil may also be used to treat hyperactivity, restlessness, anxiety, and tension. Serentil works by blocking dopaminergic transmissions in the brain.

As of 2012, Serentil is no longer available in the United States. If you live in the U.S. and are still taking this medication, you should speak with your healthcare provider about finding a suitable rep


  • How can I get the most out of my drug treatment with Serentil?
    In many cases where mental health treatment requires the use of psychotropic medication, psychotherapy may help a person achieve better, longer-lasting treatment outcomes. Medication is useful for many experiencing debilitating symptoms of mental health conditions, but does not address many of the underlying issues, behaviors, and emotions associated with mental health issues. If you are prescribed an antipsychotic medication, please consider contacting a qualified counselor or therapist to get the most out of your treatment.
  • What is the safest way to take this medication?
    Serentil comes in both tablet and liquid concentrate form; the concentrate should be diluted with a liquid such as water, orange juice, or grapefruit juice before being ingested. However, you should not dilute the concentrate with cola, coffee, or tea. The concentrate may cause irritation if it comes into contact with exposed skin. It is important to take this medication on a regular schedule, as directed by your doctor. Serentil is usually taken two to three times per day, preferably with food or milk to prevent an upset stomach. Because this drug builds up in your system gradually, it may take several weeks for you to experience its full therapeutic effect.
  • I forgot to take my medication. What should I do?
    If you miss a dose of this drug, take the missed dose as soon as you remember it. However, if you are close to your next scheduled dose, skip the missed dose completely and continue with your regular dosage schedule. If you take too much of this drug too quickly, it may lead to an overdose.
  • How do I know if I have overdosed on this drug?
    Check for signs and symptoms of overdose. These may include convulsions, high or low body temperature, agitation, erratic and uncontrollable movements, dizziness, deep sleep, irregular heartbeat, fainting, or coma.
  • What should I do if I have overdose on this drug?
    Seek emergency medical care or call a poison control center immediately.
  • What is the best way to store this medication?
    This drug should be kept tightly closed in the container it came in. Do not store this medication in locations exposed to excess heat, moisture, or light.

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